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Rochester, MN (KROC AM News) - Mayo Clinic Monday announced a major downtown Rochester expansion project that has a $200-million price tag and will create more than 100 new jobs.

The project involves a 110,000-square-foot expansion of the Mayo Clinic Proton Beam Therapy Program.

Jacobson Building/Google
Jacobson Building/Google
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Mayo says the expansion will be located on the east side of the Eisenberg Building and attached to the Jacobson Building. The expansion will include two floors below ground, a lobby level, and a first level, and be constructed to allow for future expansion.

The project will require extensive site preparation that will include the relocation of utility tunnels and pedestrian subways.

Kim David/Townsquare Media
Kim David/Townsquare Media
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Building construction is scheduled to begin in late 2022, with a goal to begin treating patients in late 2025. Existing proton beam therapy services will continue to be available during construction.

Mayo Clinic photo
Mayo Clinic photo
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Mayo says “the expansion will allow the treatment of 900 more patients per year and create 117 new jobs in a variety of roles.”

Mayo Clinic Cancer Center is the only three-site Comprehensive Cancer Center designated by the National Cancer Institute. The proton beam facilities at Mayo Clinic in Rochester and Phoenix each house their own particle accelerator that drives protons to nearly the speed of light before delivering therapeutic radiation to a patient's tumor. Plans are underway for Mayo Clinic in Jacksonville to add a facility where proton beam therapy and carbon ion therapy will be delivered to patients. Proton beam therapy will be available beginning in early 2026. Mayo Clinic in Florida will be the first carbon-ion treatment facility in North America, and it will open in 2027

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Jacobson Building/Google
Jacobson Building/Google
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